ABSTRACT Objective: This study aims to report the case of a 69-year-old female patient with a diagnosis of anorectal melanoma (AM) established by immunohistochemistry. Methods: Clinical case report, a descriptive and qualitative study. Results: The patient had a nodular and ulcerative lesion in the anal region, the imaging exams revealed an expansive lesion that affected the rectum and the vaginal wall. The chosen course of treatment was initial surgical intervention, the surgery and postoperative course progressed without complications, and the anatomopathological examination confirmed the diagnosis of invasive malignant melanoma of the distal rectum of anorectal transition. The anatomopathological examination confirmed the diagnosis of invasive malignant melanoma located in the distal rectum of the anorectal transition. Immunohistochemistry analysis showed infiltrative melanoma with microsatellites, as well as peri and intratumoral lymphocytic infiltrate, angiolymphatic invasion, and perineural invasion. The surgical resection margins, ovaries, posterior vaginal wall, and parametrium showed no signs of neoplastic involvement. Following the surgery, the patient began immunotherapy, which she is still undergoing. Conclusions: The survival rate of AM can be improved through various diagnostic and therapeutic modalities. However, further exploration of this topic through clinical studies is necessary to enhance both diagnosis and treatment.

The coronavirus (COVID-19) is a respiratory disease with a high capacity to spread. Its prevention consists of respecting social distance, wearing a mask and performing adequate hygiene of hands and surfaces, which resulted in an increase in the amount of household solid waste generated during the period of social isolation. The objective of this study is to identify the knowledge of residents of Curitiba on the management of waste contaminated or potentially contaminated by SARS-CoV-2 through an exploratory-descriptive research with a quantitative approach with 420 participants. It was found that the population's lack of knowledge about the measures contained in the municipal protocol for the prevention of contamination by the coronavirus results in an inadequate disposal of masks, gloves, handkerchiefs and napkins, even those used in a preventive way, and incorrect storage of waste from suspected cases or confirmed cases of COVID-19, which increases the risk of contamination for both the population and public servants in public cleaning.

O coronavírus (COVID-19) é uma doença de acometimento respiratório com alta capacidade de disseminação. Sua prevenção consiste em respeitar o distanciamento social, usar máscara e realizar a higienização adequada de mãos e superfícies, o que resultou em um aumento na quantidade de resíduos sólidos domiciliares gerados durante o período de isolamento social. O objetivo deste estudo é identificar o conhecimento de residentes de Curitiba sobre o manejo de resíduos contaminados ou potencialmente contaminados por SARS-CoV-2 por meio de uma pesquisa exploratória-descritiva com abordagem quantitativa com 420 participantes. Foi constatado que o desconhecimento da população acerca das medidas contidas no protocolo municipal para a prevenção da contaminação pelo coronavírus resulta em um descarte inadequado de máscaras, luvas, lenços e guardanapos, mesmo os usados de forma preventiva, e armazenamento incorreto dos resíduos de casos suspeitos ou confirmados de COVID-19, o que eleva o risco de contaminação tanto para a população como para os servidores públicos na limpeza pública.